Difficulties in Diagnosing Systemic Lupus Erythematosus in Patients of Childbearing Age: Focus on Reproductive Risks

Abstract

Systemic lupus erythematosus(SLE)-it is a multisystem autoimmune disease that mainly affects women of childbearing age. Diagnosis of SLE remains a difficult task due to the heterogeneity of the clinical picture, the absence of pathognomonic symptoms, and delayed onset of the disease during pregnancy. This article examines modern diagnostic criteria (EULAR/ACR 2019), analyzes the main diagnostic pitfalls in young women, as well as the impact of undiagnosed SLE on fertility and gestational outcomes. Special attention is paid to the differential diagnosis of preeclampsia and antiphospholipid syndrome.