Cyclodextrin in drug medication

Abstrak

Cyclodextrin molecules (CDs) are useful excipients in pharmacology in this day

and age. The main interest in CDs was gained due to their ability to interact with

hydrophobic molecules, increasing solubility in water. The high solubility is the result of

complexation through non-covalent bonding, as well as the formation of aggregates. This

review intends to give general knowledge about CDs’ shape and structure. Discuss the effect

of both host (CDs and their derivatives) and guest (drugs) molecules on complex formation.

Further part covers the application of CD-based drugs to pharmacology. As a result of this

review, the author believes that CDs will be modified to deliver complex molecules to treat

crucial diseases in the near future