HYPOTHYROIDISM AND PSYCHOEMOTIONAL FACTORS: CURRENT UNDERSTANDING OF THE MECHANISMS OF CHANGES IN THYROID-STIMULATING HORMONE

Аннотация

Hypothyroidism is a common thyroid disorder associated with changes in metabolic and neuropsychological processes. This paper aims to summarize current evidence on the diagnostic significance of thyroid-stimulating hormone (TSH) and the possible influence of psychoemotional stress on its secretion. An analytical review of clinical guidelines and scientific publications, primarily from 2024–2026, was conducted. Experimental evidence indicates that acute psychological stress may cause a short-term increase in TSH. However, a causal role for chronic stress in the development of persistent primary hypothyroidism has not been established. Interpretation of laboratory findings should take into account the clinical presentation and possible transient changes in hormone levels.