Oxygen Transport in the Human Body and Pathomorphological Changes in Its Disorders
DOI:
https://doi.org/10.5281/zenodo.19907018Keywords:
oxygen transport, hypoxia, ischaemia, pathomorphology, blood supplyAbstract
In oxygen transport and its disorders in the human body, the underlying cause is an insufficient volume of blood supply to the organs, that is, ischemia, and the lack of oxygen associated with the factors of blood supply and the condition of the blood itself. Ischemia is observed in local forms (compression, obstruction, functional spastic occlusion, venous congestion, functional mismatch in the blood supply of a working organ, anaemia after hyperaemia) and in general forms (hypoxic, anaemic and tissue hypoxia).
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1. Baloglu E., Nonnenmacher G., Seleninova A., Berg L., Velineni K., Ermis Kaya E., Mairbäurl H. The role of hypoxia-induced modulation of alveolar epithelial sodium transport in hypoxemia at high altitude. 2020.
2. Cortes-Puentes G. A., Schultz M. J., Rocco P. R. M. A narrative review on the future of acute respiratory distress syndrome: evolving definitions, mechanisms and clinical approaches. 2025.
3. Evans M., et al. Measurement of respiratory function: gas exchange and its clinical significance. 2021.
4. Guyton A. C., Hall J. E. Textbook of Medical Physiology. Elsevier, 2021.
5. Huang T. R., Chen H. L., Yang S. T., Su P. C., Hao-Wei C. The outcomes of preterm infants with neonatal respiratory distress syndrome treated by minimally invasive surfactant therapy and non-invasive ventilation. Biomedicines, 2024.
6. Lenyushkina A. A., Andreev A. V., Ionov O. V., Zubkov V. V. Review of recommendations for the care of newborns with respiratory distress syndrome. Neonatology: News, Opinions, Training, 2024.
7. Lee P., Chandel N. S., Simon M. C. Cellular adaptation to hypoxia through hypoxia-inducible factors and beyond. Nature Reviews Molecular Cell Biology, 2020.
8. O‘zbekiston Respublikasi Prezidentining 2022-yil 28-yanvardagi PF-60-son Farmoni. 2022–2026-yillarga mo‘ljallangan Yangi O‘zbekistonning taraqqiyot strategiyasi to‘g‘risida.
9. O‘zbekiston Respublikasi Prezidentining 2025-yil 19-maydagi PQ-185-son Qarori. Sog‘liqni saqlash tizimidagi islohotlarni amalga oshirish bo‘yicha chora-tadbirlar to‘g‘risida.
10. O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. Yangi tug‘ilgan chaqaloqlar respirator distress sindromini davolash bo‘yicha zamonaviy yondashuvlar. 2025.
11. O‘zbekiston Respublikasi Sog‘liqni saqlash vazirining 2025-yil 23-iyundagi 180-son buyrug‘i. Tibbiyot sohasidagi klinik-amaliy hujjatlar va tavsiyalar.
12. Pickos J., Sumner B., Franczak M., Villars M., Ghobrial M., Hickey S. M. Acute respiratory distress syndrome: deep dive into the evidence. 2020.
13. Qo‘chqarov B. V. Respirator distress sindromi va organlardagi patomorfologik o‘zgarishlar. 2025.
14. Scholkmann F., LaManna J., Wolf U., editors. Oxygen Transport to Tissue XLIII. Springer, 2022.
15. Sharma S., Hashmi M. F., Burns B. Physiology, Oxygen Transport. StatPearls. 2024.
16. Shu T., et al. Advances in acute respiratory distress syndrome: pathophysiological mechanisms and emerging therapeutic approaches. 2025
17. Simonson T. S., et al. Hypoxia and cardiorespiratory control. Frontiers in Physiology, 2021.
18. Strielkov I., Krause N. C., Sommer N. Hypoxic pulmonary vasoconstriction as a regulator of alveolar-capillary oxygen transfer. 2021.
19. Tabata C., et al. Pathophysiology, mechanisms and management of tissue hypoxia. 2022.
20. Taylor C. T., Colgan S. P. Regulation of immunity and inflammation by hypoxia in immunological niches. 2020.
21. Wu M. Z., Chen S. F., Nieh S., Benner C., Ger L. P., Jan C. I. Pathophysiological implications of hypoxia in human diseases. 2020.
22. Yangi tug‘ilgan chaqaloqlar respirator distress sindromida o‘pkasida yuzaga keladigan morfologik o‘zgarishlar. 2025.
23. Zhang L., et al. Acute respiratory distress syndrome: pathophysiological insights and therapeutic perspectives. 2025.
24. Otaboyeva M. S., Xayrullayeva M. I. Organizmdagi gazlar almashinuvida alveolalarning ahamiyati. 2025.
25. O‘pka alveolalari: ularning gistologik tuzilishi va gaz almashinuvdagi roli. Modern Science and Research, 2025.