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Tibbiyotda yetkazib beruvchi kalsiy fosfat nanozarrachalari
Annotatsiya
Kalsiy fosfat nanozarralari biologik mosligi, biologik parchalanishi, foydali
xususiyatlari va turli biologik moddalar va dorilar bilan mustahkam bog‘ hosil qilishi tufayli so‘nggi o‘n
yilliklarda dori vositalarini yetkazib berish uchun ishlatilmoqda. Masalan, nuklein kislotalar (DNK, RNK
va boshq.), oqsillar (albumin, immunoglobulinlar, osteokaltsin va boshq.) va dorilar (sisplatin,
karboplatin, doksorubitsin va boshq.). So‘nggi o‘n yilliklarda kalsiy fosfat nanotashuvchilarini
tayyorlashning sintetik usullari asosiy masala bo‘lib kelgan. Nanotashuvchilarni sintez qilish uchun turli
usullar, masalan, “flame-spray” piroliz, “sol-gel” sintezi va boshqalar joriy etilgan.
Kalit so‘zlar
Kalsiy fosfat nanozarrachalari, “flame-spray” piroliz, “sol-gel” sintezi
Foydalanilgan adabiyotlar
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2. Beigoli, S., Hekmat, A., Farzanegan, F., & Darroudi, M. (2022). Sol-gel synthesis of amorphous
calcium phosphate nanoparticles in brown rice substrate and assessment of their cytotoxicity and
antimicrobial activities. Avicenna Journal of Phytomedicine, 12(1), 77.
3. Cho, J. S., Ko, Y. N., Koo, H. Y., & Kang, Y. C. (2010). Synthesis of nano-sized biphasic
calcium phosphate ceramics with spherical shape by flame spray pyrolysis. Journal of Materials
Science: Materials in Medicine, 21(4), 1143-1149.
4. Javid-Naderi, M. J., Valizadeh, N., Banimohamad-Shotorbani, B., Shahgolzari, M., Shayegh, F.,
Maleki-baladi, R., ... & Fathi-karkan, S. (2023). Exploring the biomedical potential of iron
vanadate nanoparticles: a comprehensive review. Inorganic Chemistry Communications, 157,
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