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OLIGODENDROSITLARDAN RIVOJLANADIGAN O‘SMALAR BIOLOGIK XUSUSIYATLAR, DIAGNOSTIKASI VA YANGI DAVOLASH STRATEGIYALARI
Annotatsiya
Oligodendrositlardan rivojlanadigan o‘smalar, xususan oligodendrogliomalar, markaziy asab tizimining nisbatan kam uchraydigan, lekin klinik ahamiyati juda yuqori bo‘lgan neyroepitelial shishlaridir. Ular asosan miyaning oq moddalarida joylashadi va o‘ziga xos histologik ko‘rinishi, genetik xususiyatlari (1p/19q xromosomalar qo‘sh qo‘lini yo‘qotishi) va nisbatan yaxshi prognozi bilan ajralib turadi. So‘nggi o‘n yil ichida ushbu o‘smalarni o‘rganishda sezilarli yutuqlarga erishildi, ularning molekulyar patogenezi, diagnostikasi va davolash usullari ancha takomillashtirildi.
Kalit so‘zlar
Oligodendroglioma, 1p/19q kodelyusiya, IDH mutatsiyasi
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