Optimization of Parenteral Nutrition as a Factor in Reducing Complications in Necrotizing Enterocolitis in Newborns

Авторы

  • Mukhlisa Shavkatovna Rustamova Republican Scientific and Practical Center Автор

Ключевые слова:

necrotizing enterocolitis, newborns, parenteral nutrition, nutritional support, preterm infants, cholestasis, sepsis, short bowel syndrome, complications, neonatology

Аннотация

Necrotizing enterocolitis (NEC) is one of the most severe diseases of the neonatal period, characterized by high mortality and a significant risk of long-term complications. In conditions where enteral feeding is limited in newborns with NEC, adequate nutritional support becomes especially important. The aim of this review is to analyze current data on the role of optimizing parenteral nutrition in the prevention of metabolic disorders, infectious complications, and in improving clinical outcomes in newborns with necrotizing enterocolitis. The review discusses the features of providing requirements in proteins, lipids, carbohydrates, trace elements, and vitamins, as well as modern strategies for individualizing nutritional support. Data on the impact of balanced parenteral nutrition on reducing the incidence of sepsis, cholestasis, growth retardation, and short bowel syndrome are presented.

Опубликован

2026-11-02

Выпуск

Раздел

Articles

Как цитировать

Optimization of Parenteral Nutrition as a Factor in Reducing Complications in Necrotizing Enterocolitis in Newborns. (2026). New Innovations in National Education, 3(11). https://reandpub.uz/nine/article/view/1407

Библиографические ссылки

Neu J., Walker W.A. Necrotizing enterocolitis // New England Journal of Medicine. 2011. Vol. 364. No. 3. P. 255-264.

Frost B.L., Modi B.P., Jaksic T., Caplan M.S. New medical and surgical insights into neonatal necrotizing enterocolitis: a review // JAMA Pediatrics. 2017. Vol. 171. No. 1. P. 83-88.

Koletzko B., Goulet O., Hunt J., Krohn K., Shamir R. Guidelines on Paediatric Parenteral Nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN) // Journal of Pediatric Gastroenterology and Nutrition. 2018. Vol. 66. No. 1. P. 142-168.

Calkins K.L., Venick R.S., Devaskar S.U. Complications associated with parenteral nutrition in the neonate // Clinics in Perinatology. 2014. Vol. 41. No. 2. P. 331-345.

Niño D.F., Sodhi C.P., Hackam D.J. Necrotizing enterocolitis: new insights into pathogenesis and mechanisms // Nature Reviews Gastroenterology & Hepatology. 2016. Vol. 13. No. 10. P. 590-600.